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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Casey Sadler | 2020-2020 | .000 | 0 | 0 | 3 | 4 | 1 | 5.77 | 78 |
| Danny Salazar | 2020-2020 | .000 | 0 | 0 | 8 | 4 | 4 | 5.32 | 132 |
| Jeff Samardzija | 2020-2020 | .000 | 0 | 0 | 10 | 8 | 0 | 4.96 | 116 |
| Ali Sanchez | 2020-2020 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Anibal Sanchez | 2020-2020 | .000 | 0 | 0 | 2 | 2 | 0 | 5.03 | 33 |
| Cristopher Sanchez | 2020-2020 | .000 | 0 | 0 | 1 | 2 | 0 | 8.10 | 9 |
| Gary Sanchez | 2020-2020 | .220 | 39 | 93 | 0 | 0 | 0 | 0.00 | 0 |
| Yolmer Sanchez | 2020-2020 | .273 | 2 | 14 | 0 | 0 | 0 | 0.00 | 0 |
| Nick Sandlin | 2020-2020 | .000 | 0 | 0 | 4 | 3 | 0 | 4.43 | 61 |
| Pablo Sandoval | 2020-2020 | .173 | 3 | 13 | 0 | 0 | 0 | 0.00 | 0 |
| Miguel Sano | 2020-2020 | .233 | 55 | 124 | 0 | 0 | 0 | 0.00 | 0 |
| Carlos Santana | 2020-2020 | .243 | 24 | 95 | 0 | 0 | 0 | 0.00 | 0 |
| Danny Santana | 2020-2020 | .270 | 38 | 89 | 0 | 0 | 0 | 0.00 | 0 |
| Dennis Santana | 2020-2020 | .000 | 0 | 0 | 3 | 1 | 0 | 3.33 | 57 |
| Domingo Santana | 2020-2020 | .193 | 12 | 28 | 0 | 0 | 0 | 0.00 | 0 |
| Anthony Santander | 2020-2020 | .289 | 19 | 67 | 0 | 0 | 0 | 0.00 | 0 |
| Tony Santillan | 2020-2020 | .000 | 0 | 0 | 1 | 0 | 1 | 3.09 | 13 |
| Scott Schebler | 2020-2020 | .151 | 0 | 7 | 0 | 0 | 0 | 0.00 | 0 |
| Max Scherzer | 2020-2020 | .000 | 0 | 0 | 8 | 7 | 0 | 5.26 | 132 |
| Jonathan Schoop | 2020-2020 | .251 | 16 | 61 | 0 | 0 | 0 | 0.00 | 0 |
| Kyle Schwarber | 2020-2020 | .249 | 45 | 103 | 0 | 0 | 0 | 0.00 | 0 |
| Tanner Scott | 2020-2020 | .000 | 0 | 0 | 4 | 2 | 0 | 4.79 | 64 |
| Corey Seager | 2020-2020 | .300 | 27 | 67 | 0 | 0 | 0 | 0.00 | 0 |
| Kyle Seager | 2020-2020 | .247 | 24 | 78 | 0 | 0 | 0 | 0.00 | 0 |
| Jean Segura | 2020-2020 | .294 | 19 | 80 | 0 | 0 | 0 | 0.00 | 0 |
| Sam Selman | 2020-2020 | .000 | 0 | 0 | 4 | 2 | 2 | 3.96 | 120 |
| Marcus Semien | 2020-2020 | .300 | 28 | 98 | 0 | 0 | 0 | 0.00 | 0 |
| Antonio Senzatela | 2020-2020 | .000 | 0 | 0 | 5 | 7 | 0 | 3.94 | 99 |
| Nick Senzel | 2020-2020 | .259 | 21 | 74 | 0 | 0 | 0 | 0.00 | 0 |
| Pedro Severino | 2020-2020 | .200 | 4 | 17 | 0 | 0 | 0 | 9.00 | 1 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| Sterling Sharp | 2020-2020 | .000 | 0 | 0 | 0 | 3 | 0 | 4.05 | 30 |
| Travis Shaw | 2020-2020 | 1.000 | 1 | 1 | 0 | 0 | 0 | 0.00 | 0 |
| Justus Sheffield | 2020-2020 | .000 | 0 | 0 | 7 | 7 | 0 | 4.88 | 123 |
| Ryan Sherriff | 2020-2020 | .000 | 0 | 0 | 0 | 2 | 0 | 3.18 | 25 |
| Matt Shoemaker | 2020-2020 | .000 | 0 | 0 | 1 | 1 | 0 | 8.27 | 31 |
| Andrelton Simmons | 2020-2020 | .330 | 12 | 67 | 0 | 0 | 0 | 0.00 | 0 |
| Lucas Sims | 2020-2020 | .000 | 0 | 0 | 2 | 2 | 0 | 6.43 | 66 |
| Brady Singer | 2020-2020 | .000 | 0 | 0 | 1 | 3 | 0 | 4.61 | 66 |
| Chance Sisco | 2020-2020 | .264 | 10 | 24 | 0 | 0 | 0 | 18.00 | 1 |
| Austin Slater | 2020-2020 | .284 | 8 | 37 | 0 | 0 | 0 | 0.00 | 0 |
| Devin Smeltzer | 2020-2020 | .000 | 0 | 0 | 2 | 0 | 1 | 4.06 | 56 |
| Caleb Smith | 2020-2020 | .000 | 0 | 0 | 8 | 3 | 0 | 4.96 | 167 |
| Carson Smith | 2020-2020 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 1 |
| Dominic Smith | 2020-2020 | .203 | 6 | 27 | 0 | 0 | 0 | 0.00 | 0 |
| Drew Smith | 2020-2020 | .000 | 0 | 0 | 2 | 0 | 0 | 6.33 | 25 |
| Joe Smith | 2020-2020 | .000 | 0 | 0 | 1 | 1 | 0 | 9.15 | 28 |
| Kevan Smith | 2020-2020 | .220 | 2 | 7 | 0 | 0 | 0 | 0.00 | 0 |
| Mallex Smith | 2020-2020 | .283 | 5 | 33 | 0 | 0 | 0 | 0.00 | 0 |
| Pavin Smith | 2020-2020 | .188 | 0 | 2 | 0 | 0 | 0 | 0.00 | 0 |
| Will Smith | 2020-2020 | .000 | 0 | 0 | 1 | 2 | 6 | 4.14 | 112 |
| Will Smith | 2020-2020 | .240 | 35 | 86 | 0 | 0 | 0 | 0.00 | 0 |
| Dwight Smith Jr. | 2020-2020 | .274 | 4 | 15 | 0 | 0 | 0 | 0.00 | 0 |
| Justin Smoak | 2020-2020 | .212 | 11 | 27 | 0 | 0 | 0 | 0.00 | 0 |
| Drew Smyly | 2020-2020 | .000 | 0 | 0 | 3 | 3 | 0 | 6.25 | 68 |
| Blake Snell | 2020-2020 | .000 | 0 | 0 | 11 | 10 | 0 | 3.92 | 238 |
| Chad Sobotka | 2020-2020 | .000 | 0 | 0 | 3 | 1 | 1 | 4.17 | 85 |
| Eric Sogard | 2020-2020 | .346 | 4 | 20 | 0 | 0 | 0 | 0.00 | 0 |
| Nick Solak | 2020-2020 | .249 | 12 | 57 | 0 | 0 | 0 | 0.00 | 0 |
| Donovan Solano | 2020-2020 | .750 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 |
| Yangervis Solarte | 2020-2020 | .286 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| Jorge Soler | 2020-2020 | .255 | 41 | 108 | 0 | 0 | 0 | 0.00 | 0 |
| Joakim Soria | 2020-2020 | .000 | 0 | 0 | 6 | 4 | 7 | 3.63 | 60 |
| Mike Soroka | 2020-2020 | .000 | 0 | 0 | 12 | 10 | 0 | 4.55 | 209 |
| Juan Soto | 2020-2020 | .298 | 33 | 99 | 0 | 0 | 0 | 0.00 | 0 |
| Denard Span | 2020-2020 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| George Springer | 2020-2020 | .253 | 30 | 78 | 0 | 0 | 0 | 0.00 | 0 |
| Jacob Stallings | 2020-2020 | .235 | 0 | 3 | 0 | 0 | 0 | 0.00 | 0 |
| Craig Stammen | 2020-2020 | .000 | 0 | 0 | 2 | 1 | 0 | 5.40 | 29 |
| Ryne Stanek | 2020-2020 | .000 | 0 | 0 | 1 | 1 | 2 | 4.55 | 44 |
| Giancarlo Stanton | 2020-2020 | .230 | 55 | 120 | 0 | 0 | 0 | 0.00 | 0 |
| Bubba Starling | 2020-2020 | .143 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Cody Stashak | 2020-2020 | .000 | 0 | 0 | 0 | 2 | 1 | 4.66 | 50 |
| Max Stassi | 2020-2020 | .120 | 1 | 5 | 0 | 0 | 0 | 0.00 | 0 |
| Josh Staumont | 2020-2020 | .000 | 0 | 0 | 0 | 1 | 0 | 3.80 | 39 |
| Drew Steckenrider | 2020-2020 | .000 | 0 | 0 | 0 | 6 | 1 | 8.06 | 58 |
| Robert Stephenson | 2020-2020 | .000 | 0 | 0 | 4 | 2 | 1 | 4.76 | 117 |
| Tyler Stephenson | 2020-2020 | .231 | 3 | 10 | 0 | 0 | 0 | 0.00 | 0 |
| DJ Stewart | 2020-2020 | .167 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 |
| Kohl Stewart | 2020-2020 | .000 | 0 | 0 | 0 | 0 | 0 | 1.00 | 11 |
| Robert Stock | 2020-2020 | .000 | 0 | 0 | 5 | 0 | 2 | 4.78 | 114 |
| Trevor Story | 2020-2020 | .257 | 35 | 90 | 0 | 0 | 0 | 0.00 | 0 |
| Matt Strahm | 2020-2020 | .000 | 0 | 0 | 0 | 2 | 0 | 7.32 | 27 |
| Stephen Strasburg | 2020-2020 | .000 | 0 | 0 | 0 | 0 | 0 | 4.72 | 24 |
| Hunter Strickland | 2020-2020 | .000 | 0 | 0 | 2 | 2 | 0 | 6.07 | 16 |
| Ross Stripling | 2020-2020 | .000 | 0 | 0 | 7 | 3 | 3 | 4.32 | 94 |
| Marcus Stroman | 2020-2020 | .000 | 0 | 0 | 13 | 9 | 0 | 4.79 | 172 |
| Pedro Strop | 2020-2020 | .000 | 0 | 0 | 2 | 0 | 1 | 3.45 | 58 |
| Garrett Stubbs | 2020-2020 | .150 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 |
| Eugenio Suarez | 2020-2020 | .218 | 29 | 85 | 0 | 0 | 0 | 0.00 | 1 |
| Ranger Suarez | 2020-2020 | .000 | 0 | 0 | 0 | 0 | 0 | 9.45 | 8 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| Wander Suero | 2020-2020 | .000 | 0 | 0 | 4 | 5 | 1 | 7.17 | 68 |
| Brent Suter | 2020-2020 | .000 | 0 | 0 | 13 | 3 | 0 | 4.53 | 184 |
| Kurt Suzuki | 2020-2020 | .277 | 8 | 33 | 0 | 0 | 0 | 0.00 | 0 |
| Travis Swaggerty | 2020-2020 | .204 | 2 | 4 | 0 | 0 | 0 | 0.00 | 0 |
| Dansby Swanson | 2020-2020 | .239 | 10 | 34 | 0 | 0 | 0 | 21.00 | 2 |
| Erik Swanson | 2020-2020 | .000 | 0 | 0 | 3 | 2 | 3 | 4.24 | 102 |
| Noah Syndergaard | 2020-2020 | .000 | 0 | 0 | 14 | 7 | 0 | 3.55 | 228 |
| Thomas Szapucki | 2020-2020 | .000 | 0 | 0 | 1 | 1 | 0 | 11.57 | 10 |
