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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Casey Sadler | 2020-2020 | 3 | 4 | .429 | 5.77 | 29 | 13 | 0 | 0 | 1 | 96.2 | 118 | 62 | 8 | 19 | 78 |
| Danny Salazar | 2020-2020 | 8 | 4 | .667 | 5.32 | 49 | 8 | 1 | 0 | 4 | 94.2 | 90 | 56 | 28 | 41 | 132 |
| Jeff Samardzija | 2020-2020 | 10 | 8 | .556 | 4.96 | 31 | 1 | 0 | 0 | 0 | 118.0 | 130 | 65 | 25 | 31 | 116 |
| Anibal Sanchez | 2020-2020 | 2 | 2 | .500 | 5.03 | 9 | 6 | 0 | 0 | 0 | 39.1 | 42 | 22 | 8 | 13 | 33 |
| Cristopher Sanchez | 2020-2020 | 1 | 2 | .333 | 8.10 | 3 | 3 | 0 | 0 | 0 | 13.1 | 20 | 12 | 4 | 3 | 9 |
| Nick Sandlin | 2020-2020 | 4 | 3 | .571 | 4.43 | 40 | 0 | 0 | 0 | 0 | 44.2 | 37 | 22 | 9 | 27 | 61 |
| Dennis Santana | 2020-2020 | 3 | 1 | .750 | 3.33 | 10 | 9 | 0 | 0 | 0 | 51.1 | 51 | 19 | 6 | 19 | 57 |
| Tony Santillan | 2020-2020 | 1 | 0 | 1.000 | 3.09 | 2 | 1 | 0 | 0 | 1 | 11.2 | 9 | 4 | 3 | 1 | 13 |
| Max Scherzer | 2020-2020 | 8 | 7 | .533 | 5.26 | 25 | 25 | 0 | 0 | 0 | 131.2 | 147 | 77 | 37 | 27 | 132 |
| Tanner Scott | 2020-2020 | 4 | 2 | .667 | 4.79 | 31 | 0 | 0 | 0 | 0 | 41.1 | 31 | 22 | 3 | 30 | 64 |
| Sam Selman | 2020-2020 | 4 | 2 | .667 | 3.96 | 75 | 2 | 0 | 0 | 2 | 84.0 | 67 | 37 | 5 | 46 | 120 |
| Antonio Senzatela | 2020-2020 | 5 | 7 | .417 | 3.94 | 21 | 21 | 1 | 0 | 0 | 112.0 | 111 | 49 | 11 | 27 | 99 |
| Pedro Severino | 2020-2020 | 0 | 0 | .000 | 9.00 | 1 | 0 | 0 | 0 | 0 | 1.0 | 1 | 1 | 1 | 0 | 1 |
| Sterling Sharp | 2020-2020 | 0 | 3 | .000 | 4.05 | 12 | 5 | 0 | 0 | 0 | 40.0 | 44 | 18 | 3 | 8 | 30 |
| Justus Sheffield | 2020-2020 | 7 | 7 | .500 | 4.88 | 25 | 20 | 0 | 0 | 0 | 101.1 | 110 | 55 | 14 | 54 | 123 |
| Ryan Sherriff | 2020-2020 | 0 | 2 | .000 | 3.18 | 28 | 1 | 0 | 0 | 0 | 28.1 | 30 | 10 | 3 | 14 | 25 |
| Matt Shoemaker | 2020-2020 | 1 | 1 | .500 | 8.27 | 5 | 5 | 0 | 0 | 0 | 20.2 | 27 | 19 | 10 | 9 | 31 |
| Lucas Sims | 2020-2020 | 2 | 2 | .500 | 6.43 | 19 | 2 | 0 | 0 | 0 | 42.0 | 43 | 30 | 16 | 24 | 66 |
| Brady Singer | 2020-2020 | 1 | 3 | .250 | 4.61 | 13 | 13 | 0 | 0 | 0 | 68.1 | 78 | 35 | 15 | 18 | 66 |
| Chance Sisco | 2020-2020 | 0 | 0 | .000 | 18.00 | 1 | 0 | 0 | 0 | 0 | 1.0 | 2 | 2 | 0 | 1 | 1 |
| Devin Smeltzer | 2020-2020 | 2 | 0 | 1.000 | 4.06 | 27 | 2 | 0 | 0 | 1 | 51.0 | 45 | 23 | 9 | 17 | 56 |
| Caleb Smith | 2020-2020 | 8 | 3 | .727 | 4.96 | 26 | 21 | 0 | 0 | 0 | 118.0 | 115 | 65 | 21 | 39 | 167 |
| Carson Smith | 2020-2020 | 0 | 0 | .000 | 0.00 | 1 | 0 | 0 | 0 | 0 | 0.1 | 2 | 0 | 0 | 0 | 1 |
| Drew Smith | 2020-2020 | 2 | 0 | 1.000 | 6.33 | 20 | 0 | 0 | 0 | 0 | 27.0 | 41 | 19 | 4 | 9 | 25 |
| Joe Smith | 2020-2020 | 1 | 1 | .500 | 9.15 | 20 | 0 | 0 | 0 | 0 | 19.2 | 31 | 20 | 5 | 6 | 28 |
| Will Smith | 2020-2020 | 1 | 2 | .333 | 4.14 | 77 | 0 | 0 | 0 | 6 | 71.2 | 61 | 33 | 16 | 19 | 112 |
| Drew Smyly | 2020-2020 | 3 | 3 | .500 | 6.25 | 21 | 6 | 0 | 0 | 0 | 59.0 | 62 | 41 | 19 | 20 | 68 |
| Blake Snell | 2020-2020 | 11 | 10 | .524 | 3.92 | 30 | 30 | 1 | 0 | 0 | 190.1 | 166 | 83 | 29 | 80 | 238 |
| Chad Sobotka | 2020-2020 | 3 | 1 | .750 | 4.17 | 50 | 0 | 0 | 0 | 1 | 54.0 | 42 | 25 | 3 | 33 | 85 |
| Joakim Soria | 2020-2020 | 6 | 4 | .600 | 3.63 | 60 | 3 | 0 | 0 | 7 | 62.0 | 52 | 25 | 6 | 29 | 60 |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
| Mike Soroka | 2020-2020 | 12 | 10 | .545 | 4.55 | 33 | 33 | 0 | 0 | 0 | 194.0 | 225 | 98 | 21 | 32 | 209 |
| Craig Stammen | 2020-2020 | 2 | 1 | .667 | 5.40 | 29 | 0 | 0 | 0 | 0 | 26.2 | 31 | 16 | 6 | 7 | 29 |
| Ryne Stanek | 2020-2020 | 1 | 1 | .500 | 4.55 | 29 | 0 | 0 | 0 | 2 | 29.2 | 26 | 15 | 2 | 20 | 44 |
| Cody Stashak | 2020-2020 | 0 | 2 | .000 | 4.66 | 38 | 0 | 0 | 0 | 1 | 46.1 | 45 | 24 | 10 | 15 | 50 |
| Josh Staumont | 2020-2020 | 0 | 1 | .000 | 3.80 | 26 | 0 | 0 | 0 | 0 | 23.2 | 20 | 10 | 1 | 13 | 39 |
| Drew Steckenrider | 2020-2020 | 0 | 6 | .000 | 8.06 | 45 | 0 | 0 | 0 | 1 | 41.1 | 56 | 37 | 11 | 19 | 58 |
| Robert Stephenson | 2020-2020 | 4 | 2 | .667 | 4.76 | 82 | 0 | 0 | 0 | 1 | 73.2 | 77 | 39 | 17 | 35 | 117 |
| Kohl Stewart | 2020-2020 | 0 | 0 | .000 | 1.00 | 4 | 0 | 0 | 0 | 0 | 9.0 | 6 | 1 | 0 | 3 | 11 |
| Robert Stock | 2020-2020 | 5 | 0 | 1.000 | 4.78 | 62 | 0 | 0 | 0 | 2 | 69.2 | 64 | 37 | 12 | 37 | 114 |
| Matt Strahm | 2020-2020 | 0 | 2 | .000 | 7.32 | 12 | 1 | 0 | 0 | 0 | 19.2 | 24 | 16 | 4 | 6 | 27 |
| Stephen Strasburg | 2020-2020 | 0 | 0 | .000 | 4.72 | 3 | 3 | 0 | 0 | 0 | 13.1 | 9 | 7 | 1 | 4 | 24 |
| Hunter Strickland | 2020-2020 | 2 | 2 | .500 | 6.07 | 13 | 0 | 0 | 0 | 0 | 13.1 | 11 | 9 | 4 | 4 | 16 |
| Ross Stripling | 2020-2020 | 7 | 3 | .700 | 4.32 | 73 | 2 | 0 | 0 | 3 | 93.2 | 101 | 45 | 10 | 21 | 94 |
| Marcus Stroman | 2020-2020 | 13 | 9 | .591 | 4.79 | 33 | 33 | 0 | 0 | 0 | 193.2 | 225 | 103 | 17 | 53 | 172 |
| Pedro Strop | 2020-2020 | 2 | 0 | 1.000 | 3.45 | 49 | 0 | 0 | 0 | 1 | 47.0 | 45 | 18 | 5 | 19 | 58 |
| Eugenio Suarez | 2020-2020 | 0 | 0 | .000 | 0.00 | 2 | 0 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 1 | 1 |
| Ranger Suarez | 2020-2020 | 0 | 0 | .000 | 9.45 | 4 | 0 | 0 | 0 | 0 | 6.2 | 8 | 7 | 2 | 3 | 8 |
| Wander Suero | 2020-2020 | 4 | 5 | .444 | 7.17 | 56 | 0 | 0 | 0 | 1 | 59.0 | 71 | 47 | 9 | 27 | 68 |
| Brent Suter | 2020-2020 | 13 | 3 | .813 | 4.53 | 36 | 31 | 0 | 0 | 0 | 174.2 | 192 | 88 | 29 | 32 | 184 |
| Travis Swaggerty | 2020-2020 | 0 | 0 | .000 | 0.00 | 1 | 0 | 0 | 0 | 0 | 0.0 | 2 | 4 | 0 | 4 | 0 |
| Dansby Swanson | 2020-2020 | 0 | 0 | .000 | 21.00 | 3 | 0 | 0 | 0 | 0 | 3.0 | 10 | 7 | 1 | 2 | 2 |
| Erik Swanson | 2020-2020 | 3 | 2 | .600 | 4.24 | 38 | 0 | 0 | 0 | 3 | 57.1 | 49 | 27 | 13 | 10 | 102 |
| Noah Syndergaard | 2020-2020 | 14 | 7 | .667 | 3.55 | 31 | 31 | 1 | 1 | 0 | 190.1 | 185 | 75 | 27 | 36 | 228 |
| Thomas Szapucki | 2020-2020 | 1 | 1 | .500 | 11.57 | 2 | 2 | 0 | 0 | 0 | 7.0 | 12 | 9 | 1 | 4 | 10 |
