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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Justin Verlander# | 350 | 2020-2020 | |
| 2 | Walker Buehler# | 293 | 2020-2020 | |
| 3 | Robbie Ray# | 283 | 2020-2020 | |
| 4 | Shane Bieber# | 269 | 2020-2020 | |
| 5 | Aaron Nola# | 261 | 2020-2020 | |
| 6 | Jacob deGrom# | 260 | 2020-2020 | |
| 7 | Tyler Mahle# | 255 | 2020-2020 | |
| 8 | Jack Flaherty# | 253 | 2020-2020 | |
| 9 | Anthony DeSclafani# | 250 | 2020-2020 | |
| 10 | Lucas Giolito# | 249 | 2020-2020 | |
| 11 | Andrew Heaney# | 248 | 2020-2020 | |
| 12 | Sonny Gray# | 241 | 2020-2020 | |
| 13 | Mitch Keller# | 240 | 2020-2020 | |
| 14 | Brandon Woodruff# | 239 | 2020-2020 | |
| 15 | Lance Lynn# | 238 | 2020-2020 | |
| 15 | Blake Snell# | 238 | 2020-2020 | |
| 17 | Clayton Kershaw# | 235 | 2020-2020 | |
| 18 | Tyler Glasnow# | 234 | 2020-2020 | |
| 19 | Luke Weaver# | 232 | 2020-2020 | |
| 20 | Patrick Corbin# | 228 | 2020-2020 | |
| 20 | Kenta Maeda# | 228 | 2020-2020 | |
| 20 | Noah Syndergaard# | 228 | 2020-2020 | |
| 23 | Vince Velasquez# | 225 | 2020-2020 | |
| 24 | Frankie Montas# | 224 | 2020-2020 | |
| 25 | Mike Clevinger# | 223 | 2020-2020 | |
| 26 | Bryan Abreu# | 222 | 2020-2020 | |
| 27 | Luis Castillo# | 221 | 2020-2020 | |
| 27 | German Marquez# | 221 | 2020-2020 | |
| 27 | Joe Musgrove# | 221 | 2020-2020 | |
| 27 | Shohei Ohtani# | 221 | 2020-2020 | |
| 31 | Eduardo Rodriguez# | 219 | 2020-2020 | |
| 32 | Matthew Boyd# | 217 | 2020-2020 | |
| 32 | Jonathan Loaisiga# | 217 | 2020-2020 | |
| 34 | Chris Archer# | 215 | 2020-2020 | |
| 35 | Trevor Bauer# | 214 | 2020-2020 | |
| 36 | Chris Paddack# | 213 | 2020-2020 | |
| 37 | Framber Valdez# | 212 | 2020-2020 | |
| 38 | Jose Berrios# | 211 | 2020-2020 | |
| 38 | Kevin Gausman# | 211 | 2020-2020 | |
| 40 | Mike Soroka# | 209 | 2020-2020 | |
| 41 | Touki Toussaint# | 204 | 2020-2020 | |
| 41 | Matt Wisler# | 204 | 2020-2020 | |
| 43 | Corey Kluber# | 203 | 2020-2020 | |
| 44 | Bryse Wilson# | 201 | 2020-2020 | |
| 45 | Carlos Carrasco# | 199 | 2020-2020 | |
| 46 | A.J. Puk# | 197 | 2020-2020 | |
| 46 | Michael Wacha# | 197 | 2020-2020 | |
| 48 | Chris Bassitt# | 196 | 2020-2020 | |
| 49 | Trevor Richards# | 194 | 2020-2020 | |
| 50 | Yu Darvish# | 193 | 2020-2020 | |
| 50 | Luis Patino# | 193 | 2020-2020 | |
| 52 | Collin McHugh# | 191 | 2020-2020 | |
| 53 | Carlos Martinez# | 189 | 2020-2020 | |
| 54 | Sean Manaea# | 188 | 2020-2020 | |
| 54 | Nate Pearson# | 188 | 2020-2020 | |
| 56 | Josh James# | 186 | 2020-2020 | |
| 56 | David Price# | 186 | 2020-2020 | |
| 58 | Jacob Nix# | 184 | 2020-2020 | |
| 58 | Brent Suter# | 184 | 2020-2020 | |
| 60 | Julio Urias# | 183 | 2020-2020 | |
| 61 | Brad Keller# | 180 | 2020-2020 | |
| 62 | Dakota Hudson# | 179 | 2020-2020 | |
| 63 | Griffin Canning# | 176 | 2020-2020 | |
| 63 | Reynaldo Lopez# | 176 | 2020-2020 | |
| 63 | Jose Quintana# | 176 | 2020-2020 | |
| 66 | Caleb Ferguson# | 175 | 2020-2020 | |
| 66 | Lance McCullers Jr.# | 175 | 2020-2020 | |
| 68 | Jordan Yamamoto# | 174 | 2020-2020 | |
| 69 | Zack Wheeler# | 173 | 2020-2020 | |
| 70 | Deivi Garcia# | 172 | 2020-2020 | |
| 70 | Marcus Stroman# | 172 | 2020-2020 | |
| 72 | Zack Greinke# | 171 | 2020-2020 | |
| 72 | Jake Odorizzi# | 171 | 2020-2020 | |
| 74 | Corbin Burnes# | 170 | 2020-2020 | |
| 74 | Dallas Keuchel# | 170 | 2020-2020 | |
| 76 | Yonny Chirinos# | 168 | 2020-2020 | |
| 77 | Madison Bumgarner# | 167 | 2020-2020 | |
| 77 | Caleb Smith# | 167 | 2020-2020 | |
| 79 | Zach Davies# | 166 | 2020-2020 | |
| 80 | Luiz Gohara# | 165 | 2020-2020 | |
| 81 | Jon Gray# | 164 | 2020-2020 | |
| 82 | Gio Gonzalez# | 163 | 2020-2020 | |
| 82 | Freddy Peralta# | 163 | 2020-2020 | |
| 84 | Kyle Freeland# | 161 | 2020-2020 | |
| 84 | Kwang-hyun Kim# | 161 | 2020-2020 | |
| 84 | Alex Wood# | 161 | 2020-2020 | |
| 87 | Kyle Gibson# | 160 | 2020-2020 | |
| 87 | Adrian Houser# | 160 | 2020-2020 | |
| 87 | Mike Minor# | 160 | 2020-2020 | |
| 90 | Pablo Lopez# | 159 | 2020-2020 | |
| 91 | Yusei Kikuchi# | 158 | 2020-2020 | |
| 92 | Brent Honeywell Jr.# | 157 | 2020-2020 | |
| 93 | Junior Guerra# | 152 | 2020-2020 | |
| 93 | Trevor Rogers# | 152 | 2020-2020 | |
| 95 | Joe Ross# | 149 | 2020-2020 | |
| 96 | Johnny Cueto# | 148 | 2020-2020 | |
| 97 | Ryan Helsley# | 147 | 2020-2020 | |
| 98 | Matt Manning# | 144 | 2020-2020 | |
| 99 | Randy Dobnak# | 143 | 2020-2020 | |
| 99 | Nick Margevicius# | 143 | 2020-2020 |
