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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Mike Moustakas# | 46 | 2020 | |
| 2 | Vladimir Guerrero Jr.# | 45 | 2020 | |
| 3 | Alex Bregman# | 42 | 2020 | |
| 4 | Rafael Devers# | 39 | 2020 | |
| 5 | Matt Chapman# | 38 | 2020 | |
| 6 | Yoan Moncada# | 37 | 2020 | |
| 7 | Jose Ramirez# | 36 | 2020 | |
| 8 | Shed Long Jr.# | 35 | 2020 | |
| 9 | Nolan Arenado# | 33 | 2020 | |
| 10 | Manny Machado# | 29 | 2020 | |
| 10 | Anthony Rendon# | 29 | 2020 | |
| 10 | Eugenio Suarez# | 29 | 2020 | |
| 13 | Kris Bryant# | 26 | 2020 | |
| 14 | Jeff McNeil# | 25 | 2020 | |
| 14 | Eduardo Escobar# | 25 | 2020 | |
| 16 | Kyle Seager# | 24 | 2020 | |
| 16 | Gio Urshela# | 24 | 2020 | |
| 18 | Matt Carpenter# | 21 | 2020 | |
| 18 | Nick Senzel# | 21 | 2020 | |
| 18 | Miguel Andujar# | 21 | 2020 | |
| 18 | Ryan McMahon# | 21 | 2020 | |
| 22 | Chad Pinder# | 19 | 2020 | |
| 22 | Brian Anderson# | 19 | 2020 | |
| 24 | Justin Turner# | 18 | 2020 | |
| 25 | Johan Camargo# | 16 | 2020 | |
| 25 | Scott Kingery# | 16 | 2020 | |
| 27 | Breyvic Valera# | 7 | 2020 |
